Although some symptoms are similar, a key difference between POTS and IST is heart rate. ​
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Individuals with POTS typically have a resting heart rate of 90 bpm or less. People with IST have a resting heart rate usually greater than 100 bpm.​
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The HEAL-IST Trial is actively seeking participants with symptomatic IST and who are also resistant or intolerant to medications. ​
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IST" target="_blank">
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